Lincomycin Hydrochloride

This product is a lincomycin-based antibacterial antibiotic (lincomycin hydrochloride). It inhibits protein synthesis by binding to bacterial 50S ribosomes, resulting in high concentrations in bone tissue. It is primarily used to prevent and treat infections caused by Gram-negative bacteria and anaerobic bacteria, such as swine dysentery caused by Treponema pallidum, necrotizing enteritis, mycoplasmal pneumonia, and Mycoplasma synoviae infection in chickens.

描述

CAS No. 859-18-7
Molecular Formula: C₁₈H₃₅ClN₂O₆S

Appearance: White or off-white crystalline powder, bitter taste; readily soluble in water (>500mg/mL), soluble in methanol and ethanol, practically insoluble in chloroform and ether; aqueous solution pH≈3.0～5.5, stable.

Pharmacological Action: Lincosamide antibacterial antibiotic. Binds to bacterial 50S ribosomal subunit 23S rRNA → inhibits peptide chain translocation → blocks protein synthesis. Highly effective against Gram-negative bacteria (Streptococcus, Staphylococcus aureus, Corynebacterium pyogenes) and anaerobic bacteria (Clostridium perfringens/Clostridium perfringens); partially effective against mycoplasma; generally insensitive to Gram-negative aerobic bacteria. High concentration in bone tissue

Indications: Swine dysentery caused by *Treponema pallidum* (swine dysentery), necrotic enteritis in swine/poultry (*Clostridium perfringens*), adjunctive treatment for swine mycoplasmal pneumonia, chicken synoviae mycoplasma (in combination with aminoglycosides), soft tissue and bone infections in cattle/dogs

Storage conditions: Store in a sealed container at 2-8°C