描述
CAS No. 74610-55-2
Molecular Formula: C50H83NO23
Appearance: White to pale yellow crystalline powder, bitter taste, hygroscopic; readily soluble in water (>500mg/mL), soluble in methanol and ethanol, practically insoluble in chloroform and ether; aqueous solution pH≈5.0～7.5
Pharmacological Action: Macrolide broad-spectrum antibacterial antibiotic (bactericidal effect on some bacteria at bactericidal concentrations). Binds to bacterial 50S ribosomal subunit 23S rRNA → inhibits peptide chain translocation → blocks protein synthesis. Effective against Gram-negative bacteria (Streptococcus, Staphylococcus aureus, Corynebacterium pyogenes), Mycoplasma (highly sensitive to swine/avian Mycoplasma), some spirochetes, Vibrio, and Chlamydia; weakly effective against Gram-negative bacteria (except for a few Vibrio species). Tylosin can also be used as a growth promoter feed additive.
Indications: Mycoplasma infection in pigs/poultry (respiratory disease/CRD), infectious pleuropneumonia in pigs (in combination with florfenicol), atrophic rhinitis in pigs, mycoplasma synoviae in poultry (in combination with aminoglycosides), control of secondary bacterial infections; tylosin premixes are used to promote growth.
Storage conditions: Sealed, protected from light and moisture, store at 2-8 ℃.
