描述
CAS No. 93106-60-6
Molecular Formula: C19H22FN3O3
Appearance: Off-white to pale yellow crystalline powder, slightly bitter taste, extremely soluble in water, readily soluble in DMF, slightly soluble in methanol, practically insoluble in chloroform and ether; gradually turns pale yellow upon exposure to light.
Pharmacological Action: A third-generation fluoroquinolone broad-spectrum bactericide for animal use. It binds to the A subunit of bacterial DNA gyrase and topoisomerase IV → blocks DNA supercoiling → inhibits DNA replication, transcription, and repair → bacterial death (concentration-dependent bactericidal action). Effective against Gram-⁻ (Escherichia coli, Salmonella, Pasteurella, Haemophilus, Proteus), Gram-⁺ (Streptococcus, some strains of Staphylococcus aureus), Mycoplasma, Chlamydia, and Mycoplasma eperythrocytes; partially metabolized in vivo to ciprofloxacin (still active).
Indications: Swine/avian mycoplasmal diseases, Escherichia coli/Salmonella diarrhea, swine infectious pleuropneumonia, Haemophilus parasuis infection, bovine mastitis (Gram-negative bacteria), aquatic bacterial septicemia.
Storage conditions: Sealed, protected from light, cool and dry place (<25℃).
